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Contraindicated. CYP3A4 is to blame for the formation and elimination of cariprazine's Energetic metabolites. The result of CYP3A4 inducers on cariprazine publicity has not been evaluated and also the net result is unclear.pentobarbital will lower the extent or outcome of nelfinavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Wa